BDBM469298 US10807985, Compound 73

SMILES C[C@@H](c1ccc(F)cc1)c1cnc(nc1)N1CCN(C[C@H]1CO)c1ncnn2cc(cc12)-c1cnn(C)c1

InChI Key InChIKey=IHLMARRUBCSKMP-UUOWRZLLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469298   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM469298(US10807985, Compound 73)
Affinity DataIC50:  5.5nMAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent