BDBM469842 CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo-8-phenyl-1,3- diazaspiro[4.5]decan-3-yl]-N-(2-methoxy-pyrimidin-5-yl)-acetamide::US10807989, Example SC_1070

SMILES COc1ncc(NC(=O)CN2C[C@]3(CC[C@@](CC3)(N(C)C)c3ccccc3)N(CC3CCC3)C2=O)cn1

InChI Key InChIKey=VZMKZWAJYUVUHU-HNRBIFIRSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469842   

TargetNociceptin receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM469842(CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM469842(CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  13.5nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent