BDBM469996 CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo-8-phenyl-1,3- diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-yl-acetamide::US10807989, Example SC_1230

SMILES CN(C)[C@]1(CC[C@]2(CN(CC(=O)Nc3ccncn3)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=YJFZMTVIXGUTBH-MKPDMIMOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469996   

TargetNociceptin receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM469996(CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  1.5nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM469996(CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...)
Affinity DataKi:  36.5nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent