BDBM470126 US10807994, Compound 1.2::US10807994, Example S-2

SMILES Clc1cccc(Cl)c1N1COc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2C1=O

InChI Key InChIKey=MMAYCSIMMTVJME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470126   

TargetWee1-like protein kinase(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM470126(US10807994, Compound 1.2 | US10807994, Example S-2)
Affinity DataIC50:  3.26E+3nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen™ Terbium Labeled TR-FRET assay. Kinase assays were performed in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent