BDBM470177 US10807994, Compound 1.53::US10807994, Example S-53

SMILES COc1cc(Nc2ncc3C(=O)N(COc3n2)c2c(Cl)cccc2Cl)ccc1N1CCNCC1

InChI Key InChIKey=ADFOENVBFKRYGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470177   

TargetWee1-like protein kinase(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM470177(US10807994, Compound 1.53 | US10807994, Example S-...)
Affinity DataIC50:  33nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen™ Terbium Labeled TR-FRET assay. Kinase assays were performed in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent