BDBM470228 US10815206, Compound I-5::US11332451, Compound I-5::US11370764, Compound I-5::US11377428, Compound I-5
SMILES CCOC(=O)CCc1ccc2OC[C@H](NC(=O)c3ncn(Cc4ccccc4F)n3)C(=O)N(C)c2c1
InChI Key InChIKey=NKMUXOQHSDZDEU-IBGZPJMESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 470228
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 19.7nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 19.7nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 19.7nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 19.7nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair