BDBM470305 N-[3-(7-{1-[3-(Cyanomethyl)-1-(cyclopropylmethyl)azetidin-3-yl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10813930, Ex. No. 83

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(cnn12)-c1cnn(c1)C1(CC#N)CN(CC2CC2)C1

InChI Key InChIKey=CTAYPKMDGSFJAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470305   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM470305(N-[3-(7-{1-[3-(Cyanomethyl)-1-(cyclopropylmethyl)a...)
Affinity DataIC50:  17.5nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent