BDBM470614 US10821115, Example 18
SMILES COC(=O)c1ccc(OC[C@@]2(CNC[C@@H]3CC[C@H]3COC(C)=O)CCCc3cc(Cl)ccc23)c(Br)n1
InChI Key InChIKey=KJYOHHDPAVCNJD-OSOCVKALSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 470614
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.0600nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair