BDBM471589 US10822334, Compound 1::US10822334, Compound 24

SMILES CN1CCC(Oc2cccc3ncnc(Nc4ccc(Oc5ccn6ncnc6c5)c(C)c4)c23)C(F)(F)C1

InChI Key InChIKey=VHPDMXOIUFIAEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 471589   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471589(US10822334, Compound 1 | US10822334, Compound 24)
Affinity DataIC50:  6.86nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471589(US10822334, Compound 1 | US10822334, Compound 24)
Affinity DataIC50: >1.00E+4nMAssay Description:EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471589(US10822334, Compound 1 | US10822334, Compound 24)
Affinity DataIC50:  9.38nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471589(US10822334, Compound 1 | US10822334, Compound 24)
Affinity DataIC50: >3.00E+3nMAssay Description:EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent