BDBM471604 US10822334, Compound 16

SMILES COc1cc(O[C@H]2CCNCC2(F)F)c2c(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)ncnc2c1

InChI Key InChIKey=MGBJUGCCYZJVGR-QHCPKHFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 471604   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471604(US10822334, Compound 16)
Affinity DataIC50:  3.06E+3nMAssay Description:EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM471604(US10822334, Compound 16)
Affinity DataIC50:  10.6nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent