BDBM471701 US10822342, Compound 9

SMILES CCn1cc2nc(N)nc(-c3cn(CCCOC)c4cnc(cc34)C#CC(C)(O)C3CC3)c2n1

InChI Key InChIKey=CAMXSSKCLLVWSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471701   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471701(US10822342, Compound 9)
Affinity DataIC50:  52nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (αscreen) format (Perkin Elmer). All compounds tested were dissolv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent