BDBM472053 CIS-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl-3-(pyridin-4-yl-methyl)-1,3- diazaspiro[4.5]decan-2-one::US10829480, Example SC_2103

SMILES CN(C)[C@]1(CC[C@]2(CN(Cc3ccncc3)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=CAERYDTVNNPWIA-MKPDMIMOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472053   

TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM472053(CIS-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl...)
Affinity DataKi:  1.5nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM472053(CIS-1-(Cyclobutyl-methyl)-8-dimethylamino-8-phenyl...)
Affinity DataKi:  54nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent