BDBM472303 (S)-2-cyclopropyl-1-(1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)ethyl)-N-::US10829481, Compound I-116

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n([C@@H](C)c4cccc5OC(F)(F)Oc45)c(nc3c2)C2CC2)cc1

InChI Key InChIKey=CMKRQSPUJBFXEQ-KRWDZBQOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472303   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM472303((S)-2-cyclopropyl-1-(1-(2,2-difluorobenzo[d][1,3]d...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent