BDBM472568 US10829487, Example I-47

SMILES C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)[C@H]1C[C@@](O)(C1)C(F)(F)F)c1cccc(c1C)C(F)(F)F

InChI Key InChIKey=ZRSJETLDEMJPSO-YOEYROIRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472568   

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049]()
Boehringer Ingelheim International

US Patent
LigandPNGBDBM472568(US10829487, Example I-47)
Affinity DataIC50:  33nMAssay Description:Compounds are diluted to a final start concentration of 100 μM and are tested in duplicate. Assay-ready plates (ARPs) are generated using an Acc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent