BDBM472644 US10829487, Example I-127
SMILES C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)C1(CCOCC1)c1ccccc1)c1cccc(c1C)C(F)(F)F
InChI Key InChIKey=SNGLLGLKWYGVFJ-LJQANCHMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 472644
TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049]()
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 23nMAssay Description:Compounds are diluted to a final start concentration of 100 μM and are tested in duplicate. Assay-ready plates (ARPs) are generated using an Acc...More data for this Ligand-Target Pair