BDBM472713 US10829491, Compound S9

SMILES Nc1ncnc2n3C[C@@H](CCc3c(-c3ccc(Oc4ccccc4)cc3)c12)NS(=O)(=O)C=C

InChI Key InChIKey=MXHCJJKGWCOVGG-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472713   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute Of Materia Medica, Chinese Acad

US Patent
LigandPNGBDBM472713(US10829491, Compound S9)
Affinity DataIC50:  1.01E+4nMAssay Description:Poly(Glu, Tyr) 4:1 as a substrate for enzyme catalyzed reaction was diluted with potassium-free PBS (10 mM sodium phosphate buffer, 150 mM NaCl, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent