BDBM472740 2-amino-5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-N-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)pyrazolo[1,5-c]pyrimidine-3-carboxamide::US10829492, Example 17

SMILES CC1(C)OCC(CONC(=O)c2c(N)nn3ccc(nc23)N2CCC[C@@H]2c2cc(F)ccc2F)O1

InChI Key InChIKey=FUZLRAUTUIBKOY-FBMWCMRBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472740   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472740(2-amino-5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-...)
Affinity DataIC50: <1nMAssay Description:TrkA, TrkB and TrkC:A testing platform for TrkA, TrkB and TrkC kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent