BDBM472754 2-amino-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-thioamide::US10829492, Example 31

SMILES NC(=S)c1c(N)nn2ccc(nc12)N1CCCC1c1cc(F)ccc1F

InChI Key InChIKey=OXMXXXUBBHALNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472754   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472754(2-amino-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)p...)
Affinity DataIC50: <1nMAssay Description:TrkA, TrkB and TrkC:A testing platform for TrkA, TrkB and TrkC kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent