BDBM472769 2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-hydroxypyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US10829492, Example 47

SMILES NC(=O)c1c(N)nn2ccc(nc12)N1C[C@@H](O)C[C@H]1c1cc(F)ccc1F

InChI Key InChIKey=GERGZDJWLXJWRG-CABZTGNLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472769   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472769(2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-hydrox...)
Affinity DataIC50: <1.00E+3nMAssay Description:TrkA, TrkB and TrkC:A testing platform for TrkA, TrkB and TrkC kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent