BDBM472797 3-(((2S,3S)-3-Ethyl-4,4-difluoro-5-oxopyrrolidin-2-yl)methoxy)-5-methoxythieno[3,2-b]pyridine-6-carboxamide::US10829496, Example 1

SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)nc23)NC(=O)C1(F)F

InChI Key InChIKey=SGUQRVCNSLWDBQ-DTWKUNHWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472797   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM472797(3-(((2S,3S)-3-Ethyl-4,4-difluoro-5-oxopyrrolidin-2...)
Affinity DataIC50:  0.600nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent