BDBM472800 3-(((2S,3 S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-5-methoxybenzo[b]thiophene-6-carboxamide::US10829496, Example 4

SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC)cc23)NC(=O)[C@H]1F

InChI Key InChIKey=VWWOWLQWHHFXGW-AVZKPZGTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472800   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM472800(3-(((2S,3 S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2...)
Affinity DataIC50:  0.400nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent