BDBM472819 US10829496, Example 23

SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC(C)C)nc23)NC(=O)[C@H]1F

InChI Key InChIKey=GEWAWLWMBOMUII-PXWWUCIGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472819   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM472819(US10829496, Example 23)
Affinity DataIC50:  1.40nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent