BDBM472828 US10829500, Exam. 3

SMILES Cc1cc(cnc1C(=O)Nc1ccc(F)c(n1)[C@]1(C)C[S@@]2(=O)=NCCCCN2C(N)=N1)C#N

InChI Key InChIKey=WSSXBDLKVXUTBE-AUSOSSAASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472828   

TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM472828(US10829500, Exam. 3)
Affinity DataIC50:  36nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent