BDBM472896 Piperidin-4-ylmethyl-4-fluoro-4- (((trans-2-phenylcyclopropyl)amino) methyl)piperidine-1-carboxylate::US10836743, Compound A43

SMILES FC1(CNC2CC2c2ccccc2)CCN(CC1)C(=O)OCC1CCNCC1

InChI Key InChIKey=CMYNDDNZDLGSJZ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472896   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472896(Piperidin-4-ylmethyl-4-fluoro-4- (((trans-2-phenyl...)
Affinity DataIC50:  44.9nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472896(Piperidin-4-ylmethyl-4-fluoro-4- (((trans-2-phenyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472896(Piperidin-4-ylmethyl-4-fluoro-4- (((trans-2-phenyl...)
Affinity DataIC50:  4.21E+4nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent