BDBM472911 4-((4-fluoro-4-((((1S,2R)-2-phenyl- cyclopropyl)amino)methyl) piperidin-1-yl)methyl)benzoic acid::US10836743, Compound (1S,2R)-A5

SMILES OC(=O)c1ccc(CN2CCC(F)(CN[C@H]3C[C@@H]3c3ccccc3)CC2)cc1

InChI Key InChIKey=BBXQLXVLIQYCHN-RTWAWAEBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472911   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472911(4-((4-fluoro-4-((((1S,2R)-2-phenyl- cyclopropyl)am...)
Affinity DataIC50:  1.85E+3nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472911(4-((4-fluoro-4-((((1S,2R)-2-phenyl- cyclopropyl)am...)
Affinity DataIC50: >1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM472911(4-((4-fluoro-4-((((1S,2R)-2-phenyl- cyclopropyl)am...)
Affinity DataIC50: >1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent