BDBM473003 (R)-4-(3,3,3-trifluoropropyl)-5,6,6a,7,8,9,10,11- octahydro-[1,4]diazepino[1,2-a][1,8]naphthyridine::US10836764, Compound 157

SMILES FC(F)(F)CCc1ccnc2N3CCCNC[C@H]3CCc12

InChI Key InChIKey=PCYNOQDTYVAZBG-GFCCVEGCSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 473003   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473003((R)-4-(3,3,3-trifluoropropyl)-5,6,6a,7,8,9,10,11- ...)
Affinity DataKi:  46nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473003((R)-4-(3,3,3-trifluoropropyl)-5,6,6a,7,8,9,10,11- ...)
Affinity DataKi:  721nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473003((R)-4-(3,3,3-trifluoropropyl)-5,6,6a,7,8,9,10,11- ...)
Affinity DataKi:  1.14E+3nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent