BDBM473009 (R)-4-ethyl-3-(isopropoxymethyl)-6,6a,7,8,9,10- hexahydro-5H-pyrazino[1,2-a][1,8]naphthyridine::US10836764, Compound 163

SMILES CCc1c(COC(C)C)cnc2N3CCNC[C@H]3CCc12

InChI Key InChIKey=LTCXGMKTMVFBGU-CQSZACIVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 473009   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473009((R)-4-ethyl-3-(isopropoxymethyl)-6,6a,7,8,9,10- he...)
Affinity DataKi:  29.4nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473009((R)-4-ethyl-3-(isopropoxymethyl)-6,6a,7,8,9,10- he...)
Affinity DataKi:  47.5nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473009((R)-4-ethyl-3-(isopropoxymethyl)-6,6a,7,8,9,10- he...)
Affinity DataKi:  468nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent