BDBM473015 (R)-4-chloro-2-(methylthio)-6,6a,7,8,9,10- hexahydro-5H-pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidine::US10836764, Compound 169

SMILES CSc1nc(Cl)c2CC[C@@H]3CNCCN3c2n1

InChI Key InChIKey=GSIMGGRPVGMDAW-SSDOTTSWSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 473015   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473015((R)-4-chloro-2-(methylthio)-6,6a,7,8,9,10- hexahyd...)
Affinity DataKi:  11.2nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473015((R)-4-chloro-2-(methylthio)-6,6a,7,8,9,10- hexahyd...)
Affinity DataKi:  36.9nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM473015((R)-4-chloro-2-(methylthio)-6,6a,7,8,9,10- hexahyd...)
Affinity DataKi:  129nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent