BDBM473128 5-(8-(5-(2- hydroxypropan-2-yl)-1- methyl-1H-pyrazol-3- ylamino)imidazo[1,2- a]pyridin-6-yl)-1- methyl-1H- benzo[d]imidazol-2(3H)- one::US10842803, Structure TABLE 1.58

SMILES Cn1nc(Nc2cc(cn3ccnc23)-c2ccc3n(C)c(=O)[nH]c3c2)cc1C(C)(C)O

InChI Key InChIKey=MUWCGKRRJVQKKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473128   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473128(5-(8-(5-(2- hydroxypropan-2-yl)-1- methyl-1H-pyraz...)
Affinity DataIC50:  1.97E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent