BDBM473582 US10844062, Comparative Example 1::US10844062, Example 18

SMILES Fc1ccc(NC(=O)c2cc(cc(c2)C(F)(F)F)N2CCOCC2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=NBKSNRJGXJELHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 473582   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473582(US10844062, Comparative Example 1 | US10844062, Ex...)
Affinity DataIC50:  1.60E+3nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473582(US10844062, Comparative Example 1 | US10844062, Ex...)
Affinity DataIC50:  4.15E+3nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent