BDBM473642 US10844062, Example 78

SMILES Fc1cc(NC(=O)c2ccc(CC#N)cc2)ccc1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=CVOGGAZFOMOWEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473642   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473642(US10844062, Example 78)
Affinity DataIC50:  28nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent