BDBM473822 1-(3-Chloro-4-cyano- phenyl)-7-oxo-4,5,6,7- tetrahydro-1H- benzoimidazole-5-carboxylic acid ethyl ester::US10858342, Compound C-AAY
SMILES CCOC(=O)C1Cc2ncn(c2C(=O)C1)-c1ccc(C#N)c(Cl)c1
InChI Key InChIKey=LRUJWCMBJXFOLZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 473822
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5.10E+6nMAssay Description:Assays are performed as for aldosterone synthase except for the use of 150 units of CYP11B1, 11-deoxycortisol as substrate and cortisol measured as p...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 7.30nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair