BDBM473927 3-(6-Methoxy-1,2,3,4- tetrahydro-naphthalen-2-yl)- 6,6-dimethyl-3,5,6,7- tetrahydro-benzoimidazol-4- one::US10858342, Compound C-ACN
SMILES COc1ccc2CC(CCc2c1)n1cnc2CC(C)(C)CC(=O)c12
InChI Key InChIKey=IYYDWYKBWRGFPN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 473927
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 1.10E+7nMAssay Description:Assays are performed as for aldosterone synthase except for the use of 150 units of CYP11B1, 11-deoxycortisol as substrate and cortisol measured as p...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 24nMAssay Description:Assays are performed in 96-well format in a final volume of 60 microL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additio...More data for this Ligand-Target Pair