BDBM474149 7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydrofuran-3- yl)imidazo[1,5-a]pyrazin-8(7H)- one, stereoisomer 1::US10858362, Example 36, isomer 1::US10912773, Example 36-isomer-1::US11472810, Example 36, isomer 1

SMILES C[C@H]1OCC[C@H]1c1ncc2n1cc(C)n(Cc1cccc(F)c1)c2=O

InChI Key InChIKey=BZFPDTIGFMRZDI-CZUORRHYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 474149   

LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  152nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  59nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  152nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  59nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  152nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  59nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  152nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  59nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474149(7-(3-fluorobenzyl)-6-methyl-3-(2- methyltetrahydro...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent