BDBM474340 6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin- 10(6H)-one::US10858366, Example 1::US11453677, Example 1

SMILES Oc1c2-c3nccn3CC(C(c3ccccc3)c3ccccc3)n2ncc1=O

InChI Key InChIKey=WBNOMQYTKXNCAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474340   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474340(6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474340(6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent