BDBM474344 (S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-10H-imidazo[1,2-a]pyrido[2,1- c]pyrazin-10-one::US10858366, Example 5::US11453677, Example 5

SMILES Oc1c2-c3ncc(Cl)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O

InChI Key InChIKey=ZZAHEHWQNUVNEA-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474344   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474344((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474344((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent