BDBM474347 (S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imidazo[1,2-a]pyrido[2,1-c]pyrazin- 10(6H)-one::US10858366, Example 8::US11453677, Example 8

SMILES Oc1c2-c3ncc(C4CC4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O

InChI Key InChIKey=RFJUTKICRVWFQE-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474347   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474347((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474347((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent