BDBM474351 (S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)methyl)-11-hydroxy-5,6-dihydro-10H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin-10- one::US10858366, Example 19::US11453677, Example 19

SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3cncc(F)c3)n2ncc1=O

InChI Key InChIKey=QIKGFLNLDYAFDI-SJLPKXTDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474351   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474351((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474351((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent