BDBM474362 (S)-6-benzhydryl-11-hydroxy-3-phenyl-5,6- dihydro-10H-imidazo[1,2-a]pyrido[2,1- c]pyrazin-10-one::US10858366, Example 53::US11453677, Example 53

SMILES Oc1c2-c3ncc(-c4ccccc4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O

InChI Key InChIKey=MHWFNXWCPQNGRQ-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474362   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474362((S)-6-benzhydryl-11-hydroxy-3-phenyl-5,6- dihydro-...)
Affinity DataIC50:  60nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474362((S)-6-benzhydryl-11-hydroxy-3-phenyl-5,6- dihydro-...)
Affinity DataIC50:  60nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent