BDBM474376 (S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5,6-dihydro-10H-imidazo[1,2- a]pyrido[2,1-c]pyrazine-3-carboxamide::US10858366, Example 68

SMILES CN(C)C(=O)c1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=ZTWDNXGMOKHLGO-HXUWFJFHSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 474376   

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474376((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...)
Affinity DataEC50:  6.30E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474376((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474376((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...)
Affinity DataEC50:  3.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent