BDBM474404 1,1,1,3,3,3-Hexafluoropropan-2-yl 4-[(4-fluorophenyl)sulfonyl]-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate ::US10858373, Example 2

SMILES Fc1ccc(cc1)S(=O)(=O)N1CCOC2(CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C1

InChI Key InChIKey=BDVBVEOETSKQPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474404   

TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474404(1,1,1,3,3,3-Hexafluoropropan-2-yl 4-[(4-fluorophen...)
Affinity DataIC50:  1nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474404(1,1,1,3,3,3-Hexafluoropropan-2-yl 4-[(4-fluorophen...)
Affinity DataIC50:  7.94nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent