BDBM474411 1-{[(2-Benzoyl-2,8-diazaspiro[4.5]dec-8-yl)carbonyl]oxy}pyrrolidine-2,5-dione ::US10858373, Example 9

SMILES O=C(ON1C(=O)CCC1=O)N1CCC2(CCN(C2)C(=O)c2ccccc2)CC1

InChI Key InChIKey=KWTGKKHCVQMDJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474411   

TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474411(1-{[(2-Benzoyl-2,8-diazaspiro[4.5]dec-8-yl)carbony...)
Affinity DataIC50:  57.4nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474411(1-{[(2-Benzoyl-2,8-diazaspiro[4.5]dec-8-yl)carbony...)
Affinity DataIC50:  760nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent