BDBM474560 US10882844, Example 1019

SMILES CN1CCC(CC1)c1nc2cc(ccc2o1)-c1cccc(COc2cc(OCc3cncc(c3)C#N)c(C=O)cc2Cl)c1C

InChI Key InChIKey=XTWVJNQUBVYXMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474560   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM474560(US10882844, Example 1019)
Affinity DataIC50:  7.5nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent