BDBM474761 US10849883, Compound 186b::US11559515, Compound 186b

SMILES NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)[C@@H]2CCOC2)c2ccccc12

InChI Key InChIKey=YUIWQZVXIMTDMN-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474761   

TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474761(US10849883, Compound 186b | US11559515, Compound 1...)
Affinity DataIC50: >1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474761(US10849883, Compound 186b | US11559515, Compound 1...)
Affinity DataIC50: <1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent