BDBM474989 US10849901, Compound 39::US10953012, Example 1

SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc(cc2)[N+]([O-])=O)c1-c1ccc(Cl)cc1

InChI Key InChIKey=JCKYOIPBDDCHEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 474989   

TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474989(US10849901, Compound 39 | US10953012, Example 1)
Affinity DataIC50:  1.90nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM474989(US10849901, Compound 39 | US10953012, Example 1)
Affinity DataIC50: <1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474989(US10849901, Compound 39 | US10953012, Example 1)
Affinity DataIC50:  4.70nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent