BDBM474989 US10849901, Compound 39::US10953012, Example 1
SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc(cc2)[N+]([O-])=O)c1-c1ccc(Cl)cc1
InChI Key InChIKey=JCKYOIPBDDCHEG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 474989
Affinity DataIC50: 1.90nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix
US Patent
Bioenergenix
US Patent
Affinity DataIC50: <1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair