BDBM475409 1-(5-Bromo-1H-benzoimidazol-2-yl)-3,5-dimethyl-1H-::US10851083, Example 21::US11618744, Example 21

SMILES Cc1nn(c(C)c1C(O)=O)-c1nc2cc(Br)ccc2[nH]1

InChI Key InChIKey=SVEWJLPIGSFPEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475409   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475409(1-(5-Bromo-1H-benzoimidazol-2-yl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  6.31E+4nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475409(1-(5-Bromo-1H-benzoimidazol-2-yl)-3,5-dimethyl-1H-...)
Affinity DataIC50:  6.31E+4nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent