BDBM475449 1-[6-Chloro-5-(4-chloro-phenylsulfanyl)-1H-::US10851083, Example 61::US11618744, Example 61

SMILES OC(=O)c1cnn(c1)-c1nc2cc(Sc3ccc(Cl)cc3)c(Cl)cc2[nH]1

InChI Key InChIKey=YQFNDLDBGUHUMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475449   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475449(1-[6-Chloro-5-(4-chloro-phenylsulfanyl)-1H- | US10...)
Affinity DataIC50:  85.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475449(1-[6-Chloro-5-(4-chloro-phenylsulfanyl)-1H- | US10...)
Affinity DataIC50:  85.1nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent