BDBM475452 1-[6-Chloro-5-(3-methoxy-phenylsulfanyl)-1H-::US10851083, Example 64::US11618744, Example 64

SMILES COc1cccc(Sc2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)c1

InChI Key InChIKey=SFNJNFUGARKFDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475452   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475452(1-[6-Chloro-5-(3-methoxy-phenylsulfanyl)-1H- | US1...)
Affinity DataIC50:  126nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475452(1-[6-Chloro-5-(3-methoxy-phenylsulfanyl)-1H- | US1...)
Affinity DataIC50:  126nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent