BDBM475533 1-[6-Chloro-5-(4-methoxy-phenoxy)-1H-benzoimidazol-::US10851083, Example 145::US11618744, Example 145

SMILES COc1ccc(Oc2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1

InChI Key InChIKey=IKHYTXRXRQOKLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475533   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475533(1-[6-Chloro-5-(4-methoxy-phenoxy)-1H-benzoimidazol...)
Affinity DataIC50:  79.4nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475533(1-[6-Chloro-5-(4-methoxy-phenoxy)-1H-benzoimidazol...)
Affinity DataIC50:  79.4nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent