BDBM475537 1-(5-Ethylsulfanyl-6-trifluoromethyl-1H-benzoimidazol-2-::US10851083, Example 149::US11618744, Example 149

SMILES CCSc1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O

InChI Key InChIKey=ICCAPIMPXFYEEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475537   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475537(1-(5-Ethylsulfanyl-6-trifluoromethyl-1H-benzoimida...)
Affinity DataIC50:  50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475537(1-(5-Ethylsulfanyl-6-trifluoromethyl-1H-benzoimida...)
Affinity DataIC50:  50.1nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent